Can Bioactive Lipids Inactivate Coronavirus (COVID-19)?
Identifieur interne : 000884 ( 2020/Analysis ); précédent : 000883; suivant : 000885Can Bioactive Lipids Inactivate Coronavirus (COVID-19)?
Auteurs : Undurti N. Das [États-Unis]Source :
- Archives of medical research [ 1873-5487 ] ; 2020.
Abstract
SARS-CoV-2, SARS and MERS are all enveloped viruses that can cause acute respiratory syndrome. Arachidonic acid (AA) and other unsaturated fatty acids (especially eicosapentaenoic acd, EPA and docosahexaenoic acid DHA) are known to inactivate enveloped viruses and inhibit proliferation of various microbial organisms. The pro-inflammatory metabolites of AA and EPA such as prostaglandins, leukotrienes and thromboxanes induce inflammation whereas lipoxins, resolvins, protectins and maresins derived from AA, EPA and DHA not only suppress inflammation but also enhance would healing and augment phagocytosis of macrophages and other immunocytes and decrease microbial load. In view of these actions, it is suggested that AA and other unsaturated fatty acids and their metabolites may serve as endogenous anti-viral compounds and their deficiency may render humans susceptible to SARS-CoV-2, SARS and MERS and other similar viruses' infections. Hence, oral or intravenous administration of AA and other unsaturated fatty acids may aid in enhancing resistance and recovery from SARS-CoV-2, SARS and MERS infections.
DOI: 10.1016/j.arcmed.2020.03.004
PubMed: 32229155
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000445
- to stream PubMed, to step Curation: 000445
- to stream PubMed, to step Checkpoint: 000700
- to stream Ncbi, to step Merge: 003646
- to stream Ncbi, to step Curation: 003646
- to stream Ncbi, to step Checkpoint: 003646
- to stream Main, to step Merge: 000884
- to stream Main, to step Curation: 000884
- to stream Main, to step Exploration: 000884
- to stream 2020, to step Extraction: 000884
Links to Exploration step
pubmed:32229155Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Can Bioactive Lipids Inactivate Coronavirus (COVID-19)?</title><author><name sortKey="Das, Undurti N" sort="Das, Undurti N" uniqKey="Das U" first="Undurti N" last="Das">Undurti N. Das</name><affiliation wicri:level="2"><nlm:affiliation>UND Life Sciences, Battle Ground, WA. Electronic address: Undurti@hotmail.com.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Washington (État)</region></placeName><wicri:cityArea>UND Life Sciences, Battle Ground</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32229155</idno><idno type="pmid">32229155</idno><idno type="doi">10.1016/j.arcmed.2020.03.004</idno><idno type="wicri:Area/PubMed/Corpus">000445</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000445</idno><idno type="wicri:Area/PubMed/Curation">000445</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000445</idno><idno type="wicri:Area/PubMed/Checkpoint">000700</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000700</idno><idno type="wicri:Area/Ncbi/Merge">003646</idno><idno type="wicri:Area/Ncbi/Curation">003646</idno><idno type="wicri:Area/Ncbi/Checkpoint">003646</idno><idno type="wicri:Area/Main/Merge">000884</idno><idno type="wicri:Area/Main/Curation">000884</idno><idno type="wicri:Area/Main/Exploration">000884</idno><idno type="wicri:Area/2020/Extraction">000884</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Can Bioactive Lipids Inactivate Coronavirus (COVID-19)?</title><author><name sortKey="Das, Undurti N" sort="Das, Undurti N" uniqKey="Das U" first="Undurti N" last="Das">Undurti N. Das</name><affiliation wicri:level="2"><nlm:affiliation>UND Life Sciences, Battle Ground, WA. Electronic address: Undurti@hotmail.com.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Washington (État)</region></placeName><wicri:cityArea>UND Life Sciences, Battle Ground</wicri:cityArea></affiliation></author></analytic><series><title level="j">Archives of medical research</title><idno type="eISSN">1873-5487</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">SARS-CoV-2, SARS and MERS are all enveloped viruses that can cause acute respiratory syndrome. Arachidonic acid (AA) and other unsaturated fatty acids (especially eicosapentaenoic acd, EPA and docosahexaenoic acid DHA) are known to inactivate enveloped viruses and inhibit proliferation of various microbial organisms. The pro-inflammatory metabolites of AA and EPA such as prostaglandins, leukotrienes and thromboxanes induce inflammation whereas lipoxins, resolvins, protectins and maresins derived from AA, EPA and DHA not only suppress inflammation but also enhance would healing and augment phagocytosis of macrophages and other immunocytes and decrease microbial load. In view of these actions, it is suggested that AA and other unsaturated fatty acids and their metabolites may serve as endogenous anti-viral compounds and their deficiency may render humans susceptible to SARS-CoV-2, SARS and MERS and other similar viruses' infections. Hence, oral or intravenous administration of AA and other unsaturated fatty acids may aid in enhancing resistance and recovery from SARS-CoV-2, SARS and MERS infections.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Washington (État)</li></region></list><tree><country name="États-Unis"><region name="Washington (État)"><name sortKey="Das, Undurti N" sort="Das, Undurti N" uniqKey="Das U" first="Undurti N" last="Das">Undurti N. Das</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/2020/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000884 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/2020/Analysis/biblio.hfd -nk 000884 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= 2020
|étape= Analysis
|type= RBID
|clé= pubmed:32229155
|texte= Can Bioactive Lipids Inactivate Coronavirus (COVID-19)?
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/2020/Analysis/RBID.i -Sk "pubmed:32229155" \
| HfdSelect -Kh $EXPLOR_AREA/Data/2020/Analysis/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |